Global analysis of the nuclear processing of transcripts with unspliced U12-type introns by the exosome.

Nucleic Acids Res · 2014 · PMC4066798 · PMID 24848017

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closest p · 0.0× alpha

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boldest claim

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highly significantP < 2.2E−16actually significant

Importantly, the global shift observed with RRP41 knockdown was statistically highly significant ( P < 2.2E−16, Jonckheere trend test) and was not observed with the U2-type introns located immediately up- or downstream of the U12-type introns (Figure 3F ) or in the group of all the U2-type introns in the same genes.

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