The model is clear and the investigators have done an excellent job integrating the biochemical cycle of the ParComplex with the fluctuations of DNA into a novel mechanism that provides highly significant insight into an important biological problem. 10.7554/eLife.02758.031 Author response In short, we would like to receive a revised manuscript that addresses the major point raised by Reviewer # 1, to provide additional evidence for elastic dynamics in other regions of the Caulobacter chromosomes and to expand the scope of the modeling, as suggested by Reviewer #2.
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Evidence for a DNA-relay mechanism in ParABS-mediated chromosome segregation.
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