A GPBAR1 (TGR5) small molecule agonist shows specific inhibitory effects on myeloid cell activation in vitro and reduces experimental autoimmune encephalitis (EAE) in vivo.

PLoS One · 2014 · PMC4072711 · PMID 24967665

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highly significantno p-value reported

5B ) and found a highly significant reduction (84% & 88%, respectively).

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