trend toward significancep = 0.059
Furthermore, there are inverse correlations that trend toward significance between levels of LPS or sCD14 and claudin transcript expression in the descending colon of both HIV+ and healthy control subjects (r = −0.79, p = 0.059 for claudin-4 vs. sCD14; and r = −0.76, p = 0.073 for claudin-2 vs.