Hypermethylation in the ZBTB20 gene is associated with major depressive disorder.

Genome Biol · 2014 · PMC4072999 · PMID 24694013

Europe PMC DOI

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highly significantP < 2.2 × 10 -16actually significant

Comparison of variance in global methylation between the depressed twin and their unaffected co-twin revealed a highly significant increased genome-wide variance in twins with MDD in both the UK and Australian cohorts ( P < 2.2 × 10 -16 in both datasets).

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