When quantified with the MNGC analysis pipeline we could detect significant differences between the Bp K96243 (wt) and the mock infected samples in terms of mean Number of Spots per Clusters, Cluster Area and marginally significant differences in terms of mean Percentage of MNGC (Figure 3 B).
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A high-content imaging assay for the quantification of the Burkholderia pseudomallei induced multinucleated giant cell (MNGC) phenotype in murine macrophages.
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