QSAR-based models for designing quinazoline/imidazothiazoles/pyrazolopyrimidines based inhibitors against wild and mutant EGFR.

PLoS One · 2014 · PMC4081576 · PMID 24992720

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highly significantno p-value reported

Feature selection As the selection of best and highly significant descriptors is crucial for QSAR modeling, feature selection was carried out to eliminate highly correlated descriptors, multicollinearity and remove useless descriptors.

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