The Par3-like polarity protein Par3L is essential for mammary stem cell maintenance.

Nat Cell Biol · 2014 · PMC4083567 · PMID 24859006

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highly significantno p-value reported

These data indicate that silencing of Par3L causes a highly significant ~100-fold decrease in functional MRUs.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.