As shown in Supplementary Table S1 (column ‘WR score with conservation’), in all cases tested we have detected a significant enrichment of the mapped motifs in the set of the strong binders (ranked highest in the CLIP experiments) with highly significant p-values, ranging from 6.56e −9 to 3.97e −207 and an average sensitivity and specificity of 0.61 (±0.18) and 0.74 (±0.11), respectively.
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