highly significantP < 0.001
Both groups showed a highly significant decrease in INR values over time (reversal: 1.3 ± 0.2 at 180 ± 31 min after PCC application vs bleeding: 1.2 ± 0.2 at 147 ± 15 min after treatment; INR: P < 0.001 vs baseline, time: not significant).