Barely Significant
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Co-isolation of extracellular vesicles and high-density lipoproteins using density gradient ultracentrifugation.

J Extracell Vesicles · 2014 · PMC4090368 · PMID 25018865

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may be significantno p-value reported
As EVs will be present in such fractions, and because EVs are known to expose proteins involve in complement activation ( 11 , 12 ), the contribution of EVs in such proteomics studies may be significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.