Activity and architecture of pyroglutamate-modified amyloid-β (AβpE3-42) pores.

(Note the additional grouping around 600 pS.) Table 1 shows that the average conductance in this third region is ∼20% higher for Aβ pE3-42 . These results show an overall trend for higher Aβ pE3-42 conductance, which could have relevance to the Aβ pE3-42 toxicity mechanism.

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