Catridecacog: a breakthrough in the treatment of congenital factor XIII A-subunit deficiency?

84 However, bleeding might still occur 65 and might be significant (eg, if surgical stress is applied); therefore, higher-than-prophylactic levels are recommended in FXIII-deficient patients undergoing surgery. 63 , 85 In pregnancy, more frequent replacements with lower doses have been reported to be successful, 69 which is important, as pregnant women with severe

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