Trace amines inhibit insect odorant receptor function through antagonism of the co-receptor subunit.

Highly significant inhibition (p<0.001) was also observed for phenethylamine (41 ± 1%), tyramine (40 ± 5%), gramine (30 ± 4%) and serotonin 23 ± 3%), but the extent of inhibition was less than 50%, suggesting relatively low affinity interactions.

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