Interestingly, a highly significant correlation was found between the levels of GrB and IFN- γ produced by Leishmania antigen-stimulated PBMCs (Spearman's rank correlation coefficient; r = 0.816, P < 0.0001), ( data not shown ). 3.2.
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Involvement of different CD4(+) T cell subsets producing granzyme B in the immune response to Leishmania major antigens.
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