While a reduction in gametocyte numbers alone would be difficult to interpret given the different infection courses of wild type and mutant parasites, a reduction in the ability of each microgametocyte to release microgametes and of macrogametes to convert to ookinetes is highly significant.
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BCKDH: the missing link in apicomplexan mitochondrial metabolism is required for full virulence of Toxoplasma gondii and Plasmodium berghei.
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