Prions: generation and spread versus neurotoxicity.

J Biol Chem · 2014 · PMC4106307 · PMID 24860100

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highly significantno p-value reported

Importantly, targeted expression of GADD34 and focal PrP knockdown had a modest, but highly significant, effect on survival.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.