Additional analyses of all Aβ data by Fisher’s least significance test accounting for data with very strong progression, revealed a highly significant increase of soluble Aβ38, Aβ40 and Aβ42 as well as insoluble Aβ40 and Aβ42 levels in the hippocampus and neocortex of APP SL mice (Figure 1 and Additional file 4 ).
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Neuroinflammation and related neuropathologies in APPSL mice: further value of this in vivo model of Alzheimer's disease.
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