The Roles of Mechanical Stresses in the Pathogenesis of Osteoarthritis: Implications for Treatment of Joint Injuries.

In the specific case of articular surface impaction injuries, acute contusion of the cartilage may or may not be associated with clinically detectable articular surface fracture even though there may be significant cell death. 50 As regards habitual articulation abnormalities responsible for gradual onset of progressive tissue damage and degradation after joint trauma, 2 common manifestations are joint instability and residual articular incongruity, both of which involve well-documented levels of chronic local contact stress elevation. 9 , 51 - 53 Acute high-intensity joint injuries that initiate joint degeneration involve damage of the articular surface.

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