Q192R SNP, insulin resistance, and endothelial dysfunction Some final comment deserves the weaker and borderline significant strength of the association of the Q192R polymorphism with endothelial dysfunction as compared with the highly significant and quantitatively stronger link with insulin resistance.
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Q192R Paraoxonase (PON)1 Polymorphism, Insulin Sensitivity, and Endothelial Function in Essential Hypertensive Men.
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The sentences
When the same analysis was applied on endothelial dysfunction, only the Q192R genotype (OR: 0.34, 95% CI: 0.11–1.07, P = 0.054, Q/Q as referent) played a borderline significant role.