The p85 regulatory subunit of PI3K mediates cAMP-PKA and insulin biological effects on MCF-7 cell growth and motility.

ScientificWorldJournal · 2014 · PMC4119716 · PMID 25114970

Europe PMC DOI

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highly significantno p-value reported

This study demonstrates that the overexpression of p85A induces a highly significant suppression of MCF-7 cells motility, indicating that the phosphorylation of p85 α PI3K S83 is a critical regulator of this process.

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