Directing human induced pluripotent stem cells into a neurosensory lineage for auditory neuron replacement.

Although it is difficult to conclusively determine the exact cause of the variabilities observed between the hiPSC and hESC lines, it is possible that a combination of intrinsic cell line specific variabilities and/or the presence of genomic and epigenetic instabilities in the hiPSCs may be significant contributing factors.

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However, at 35 DIV, an overall trend of increasing GATA3 expression was detected, particularly in the iPS2 cell line.

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