A physically-modified saline suppresses neuronal apoptosis, attenuates tau phosphorylation and protects memory in an animal model of Alzheimer's disease.

PLoS One · 2014 · PMC4121132 · PMID 25089827

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markedly significantp<0.000not a probability at all

We noticed markedly significant improvement F (3,24) = 56.282, p<0.000 in short-term memory ( Fig. 11I ) as evidenced by discrimination index (i.e the difference between time spent exploring novel and familiar objects during test phase) in RNS60 treated 5XFAD mice as compared to untreated or NS-treated 5XFAD, but, 5XFAD mice showed profound impairment (p<0.000) as compared to age matched non-Tg mice.

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