Mutation of the melastatin-related cation channel, TRPM3, underlies inherited cataract and glaucoma.

PLoS One · 2014 · PMC4121231 · PMID 25090642

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highly significantno p-value reported

Moreover, when we tested the c.195A>G change as a bi-allelic marker with a notional frequency of 1% in a two-point LOD score analysis we obtained highly significant confirmation of linkage to TRPM3 (Z max = 9.51, θ max = 0.0) ( Table 1 ).

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