Apogossypolone inhibits the proliferation of LNCaP cells in vitro and in vivo.

Mol Med Rep · 2014 · PMC4121422 · PMID 25060748

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highly significantno p-value reported

A reagent with a T/C% <10% is considered to have highly significant anti-tumor activity and this is also the criteria used by the NCI to justify a clinical trial ( 12 ).

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an increasing trendno p-value reported

Furthermore, the incidence rate and the morality rate of the prostatic cancers also show an increasing trend year after year.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.