Although treatment of MCAO using four daily injections of 100 μg RTL1000 produced highly significant reductions in infarct volumes in both females (current study) and males [ 15 ], successful treatment of MCAO with the DRα1 construct given daily for 4 days required a higher dose in females (1 mg) than in males (100 μg).
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Novel humanized recombinant T cell receptor ligands protect the female brain after experimental stroke.
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