Syndecan-1 is required to maintain intradermal fat and prevent cold stress.

PLoS Genet · 2014 · PMC4125098 · PMID 25101993

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highly significantno p-value reported

These mice do show highly significant phenotypes such as tumor resistance [16] , [17] , altered stress responses and wound healing, and changes in B cell development and microbial pathogenesis [18] .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.