Barely Significant
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Bone temperature during cementation with a heatsink: a bovine model pilot study.

BMC Res Notes · 2014 · PMC4126909 · PMID 25099248

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may be significantno p-value reported
Interestingly one study using ovine models found that thermonecrosis did not occur despite temperatures exceeding 49.3° [ 11 ] although this contradicts several other papers which suggest that thermally induced bone injury may be significant [ 5 , 6 , 12 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.