highly significantP ≤ 0.05
* P ≤ 0.05 represents significant difference compared to control (−ve control) and ** P ≤ 0.01 represents highly significant differences compared to control (−ve control). a P ≤ 0.05 represents significant difference compared to METH (+ve control) group. b P ≤ 0.01 represents highly significant difference compared to METH (+ve control) group. 3.