Mesenchymal cell interaction with ovarian cancer cells induces a background dependent pro-metastatic transcriptomic profile.

SKOV3 co-cultured with MSC resemble some human tumors To determine whether the highly significant expression changes seen after cell lines are co-cultured with MSCs could have some clinical relevance, we calculated the similarity (Pearson’s correlation coefficient) between the expression changes for each cell line and publically available human ovarian cancer expression data from 493 patients.

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