Barely Significant
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Clinical efficacy and treatment persistence of monthly minodronate for osteoporotic patients unsatisfied with, and shifted from, daily or weekly bisphosphonates: the BP-MUSASHI study.

Osteoporos Int · 2014 · PMC4134483 · PMID 24899103

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a decreasing trendno p-value reported
In all subgroups, VAS scores demonstrated a decreasing trend after switching, with the decreases in the subgroups of patients who switched from alendronate and daily dose of minodronate statistically significant at 1 month after treatment and subsequent time points ( p < 0.05).

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