The frequency of IFN-γ+ cells was significantly increased both in CD4+T ( P = 0.0186) cells and CD8+T ( P = 0.0759) cells from IL-17A −/− IL-2Rα −/− mice compared to IL-2Rα −/− mice, although there is only a trend toward significance in CD8+T cells ( Figure 6C ).
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Differential modulation by IL-17A of Cholangitis versus Colitis in IL-2Rα deleted mice.
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