The flavones apigenin and luteolin induce FOXO1 translocation but inhibit gluconeogenic and lipogenic gene expression in human cells.

PLoS One · 2014 · PMC4138109 · PMID 25136826

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failed to reach significanceno p-value reported

PEPCK mRNA levels were lowered upon double knockdowns of FOXO3a/SIRT1 (p = 0.049) but FOXO3a alone did not show any effect and a faint reduction by SIRT1 knockdown failed to reach significance.

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