Adenosine A2A receptors modulate acute injury and neuroinflammation in brain ischemia.

Mediators Inflamm · 2014 · PMC4138795 · PMID 25165414

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highly significantno p-value reported

Moreover Sheardown and Knutsen [ 45 ] demonstrated that a high dose of the selective A 2A receptor agonist, CGS21680 (10 mg/kg i.p.), administered after 5 min of global ischemia in gerbil, exhibited highly significant protection against neuronal loss, but was inactive at 3 mg/kg.

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