cruzi genome databases of currently sequenced strains in the NCBI genomes and refseq databases ( http://www.ncbi.nlm.nih.gov/refseq ) revealed highly significant identity between the epitope recognized by MAb 4A4 and many surface proteins from multiple geographically diverse T. cruzi strains typically present in Brazil, Argentina, Chile, Venezuela, Bolivia, Colombia and Mexico (Pratap et. al. , 2014 manuscript in preparation) [69] , [70] .
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Immunization with Hexon modified adenoviral vectors integrated with gp83 epitope provides protection against Trypanosoma cruzi infection.
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