Progesterone receptor expression declines in the guinea pig uterus during functional progesterone withdrawal and in response to prostaglandins.

We did not encounter high enough number of unilateral pregnancies to determine gestational changes in receptor levels in the non-pregnant horns, but a recent study using experimentally growth restricted pregnant animals detected a decreasing trend of PR expression in both the gravid and the non-gravid uterine horns at late gestation [24] .

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