The concentration of another pro-inflammatory cytokine, TNF-α, showed a borderline significant down-modulation after combination treatment as compared to control group (KWT Bonferroni adjusted P -value: 0.08, Figure 4B ).
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Histone deacetylase inhibitor-temozolomide co-treatment inhibits melanoma growth through suppression of Chemokine (C-C motif) ligand 2-driven signals.
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