Theoretical basis, laboratory evidence, and clinical research of chemical surgery of the cornea: cross-linking.

In another study, Wollensak and Iomdina (2009) found a highly significant increase in corneal stiffness after CXL treatment of rabbit corneas with an impressive durability over time, as demonstrated by a 78.4%–87.4% (by a factor of 1.6) increase in Young's modulus by and a 69.7%–106.0% increase in ultimate stress over the entire 8-month follow-up [ 21 ].

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