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Urinary nerve growth factor could be a biomarker for interstitial cystitis/painful bladder syndrome: a meta-analysis.

PLoS One · 2014 · PMC4152268 · PMID 25181532

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an increasing trendno p-value reported
The results of Rachaneni's systematic review [37] suggest an increasing trend of NGF in DO patients compared to controls.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.