Baseline CD4+ T cell counts correlates with HIV-1 synonymous rate in HLA-B*5701 subjects with different risk of disease progression.

PLoS Comput Biol · 2014 · PMC4154639 · PMID 25187947

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highly significantno p-value reported

The analysis of longitudinal viral sequences with advanced computational biology techniques based on coalescent Bayesian methods showed a highly significant association between lower synonymous substitution rates and higher baseline CD4 + T cell counts in HLA-B*5701 subjects.

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