Transcription factor-pathway coexpression analysis reveals cooperation between SP1 and ESR1 on dysregulating cell cycle arrest in non-hyperdiploid multiple myeloma.

The meta-analysis down-weights TrF-pathway co-expression patterns specific to one data set, even if this pattern may be significant in the data set ( Figure 3A ); and enhances the patterns consistent across data sets but may not be significant in any one data set ( Figure 3B ).

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