Laser-scanning astrocyte mapping reveals increased glutamate-responsive domain size and disrupted maturation of glutamate uptake following neonatal cortical freeze-lesion.

Front Cell Neurosci · 2014 · PMC4158796 · PMID 25249939

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Astrocytes in the neonatal sham and FL cortex showed a small, but highly significant acceleration of the TC decay time at distal locations compared to the soma (distal T 1/2 time constants of glutamate evoked current normalized to decay kinetics at somatic locations: neonatal sham 0.83 ± 0.04, neonatal FL 0.71 ± 0.07).

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