Two phase I dose-escalation/pharmacokinetics studies of low temperature liposomal doxorubicin (LTLD) and mild local hyperthermia in heavily pretreated patients with local regionally recurrent breast cancer.

Int J Hyperthermia · 2014 · PMC4162656 · PMID 25144817

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may be significantno p-value reported

However, there may be significant concerns with soft tissue and bone injury along with potential cardiac toxicity in the setting of left side CWR.

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