An experimentally informed evolutionary model improves phylogenetic fit to divergent lactamase homologs.

Mol Biol Evol · 2014 · PMC4166927 · PMID 25063439

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a slight trendno p-value reported

There appears to be a slight trend for improvements due to the experimentally informed models to be most common for buried sites, but the experimentally informed models lead to small improvements for sites spanning a range of solvent accessibilities and secondary structures.

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