This does not take into account rectal movements during the actual treatment fraction, which may be significant and may depend on the overall treatment time. 42 , 43 Variation in contouring A single clinician provided all contours for this study; this eliminated uncertainty owing to interobserver variability in contouring.
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Random variation in rectal position during radiotherapy for prostate cancer is two to three times greater than that predicted from prostate motion.
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