Barely Significant
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Large chromosomal rearrangements during a long-term evolution experiment with Escherichia coli.

mBio · 2014 · PMC4173774 · PMID 25205090

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The sentences

highly significantP = 3 × 10 −21actually significant
This overrepresentation of prophage DNA is highly significant (binomial test, P = 3 × 10 −21 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.