Instillation versus inhalation of multiwalled carbon nanotubes: exposure-related health effects, clearance, and the role of particle characteristics.

However, given that a 200 μg dose of O- or P-MWCNTs produced highly significant particle-associated inflammation, and a 50 μg instillation of MWCNTs was sufficient to produce neutrophilia and significant MWCNT-positive macrophages (in contrast to control), it is possible we would have seen acute inflammation by histopathology in animals given 50 μg of O- or P-MWCNTs too.

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