Synonymous codon bias and functional constraint on GC3-related DNA backbone dynamics in the prokaryotic nucleoid.

Nucleic Acids Res · 2014 · PMC4176184 · PMID 25200075

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Across all 27 examples of the dapL genes, representing all major domains of the tree of life, the role of synonymous codon bias in altering the flexibility of the coding region was strong and highly significant ( r = 0.836, P < 0.001; Figure 6A ).

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