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Selection at the Esterase-2 locus of Drosophila buzzatii? Perturbation-reperturbation experiments.

PLoS One · 2014 · PMC4176962 · PMID 25250904

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a decreasing trendno p-value reported
Cages 16R3 – 19R3 (also derived from 16R1-19R1) also show a decreasing trend in p ( a ), but were not maintained for long enough to detect definite trends.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.