highly significantP<0.001
In all cases, target transcript knockdowns had developed to highly significant levels by the end of this maintenance period (FheCatB: 0.09±0.02, P<0.001, n = 4; FheCatL: 0.18±0.08, P<0.001, n = 5; FheσGST: 0.18±0.06, P<0.001, n = 4; Figure 3B–D ).